YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
ステロイドホルモンの研究 (第1報)
卵黄油不鹸化物中に存在する発情性物質について その1
滝川 泱男小野 惠子
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1953 年 73 巻 2 号 p. 180-184

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1) Oil of egg yolk was saponified with alcoholic potash and separated into non-saponifiable matter and acid substance.
2) A ketosteroid was obtained from the non-saponifiable matter as white needle crystals, m.p. 142-143°, which gave a semicarbazone of m.p. 258-260°, and an oxime of m.p. 188-190°.
3) The above ketosteroid gave a positive vaginal smear reaction in young female mice, and caused the increase of the weight of seminal vesicles and prostatic glands in castrated male mice.
4) The acid portion was composed of liquid acids containing oleic, linolic, and higher unsaturated fatty acids, and solid acids containing palmitic and stearic acid.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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