YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
サルファ剤の分子化合物に就いて
内藤 多喜夫白井 秀明織田 範一
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ジャーナル フリー

1953 年 73 巻 7 号 p. 663-665

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Manner of the formation of molecular compounds between p-aminomethylbenzene-sulfonamide (Homosulfamine) and sulfa drugs, and between sulfa drugs was examined by thermal analysis. The formation of molecular compounds was detected between Homosulfamine and sulfacetamide, sulfathiazole, phthalylsulfathiazole, sulfadiazine, Irgafen, and sulfisoxazole, and between diaminodiphenyl sulfone and sulfanilylthiourea. The molecular compounds are obtained as crystals from suitable solvents and their solubilities were found to be much greater than those of original sulfa drugs.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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