YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Solubilizationの製剤学への応用 (第2報)
2-Methyl-1,4-naphthoquinoneのSolubilization
中川 俊夫
著者情報
ジャーナル フリー

1953 年 73 巻 7 号 p. 732-736

詳細
抄録

Solubility of 2-methyl-1, 4-naphthoquinone in the aqueous solution of nonionic surface-active agents possessing a polyoxyethylene group was determined and following characteristics were observed. The solubility of 2-methyl-1, 4-naphthoquinone was approximately proportional to the concentration of the surface-active agent but the solubilizing efficiency was better at a lower concentrations. At a very high concentration region of the active agent, the solubilizing efficiency was found to increase rapidly. Compared in the same weight/volume concentration, active agents with less oxyethylene group possessed better solubilizing efficiency. These results were compared with the solubility in an aqueous solution of a few ionic surface-active agents and simple observations were made.

著者関連情報
© by the PHARMACEUTICAL SOCIETY OF JAPAN
前の記事 次の記事
feedback
Top