YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
合成鎭痛剤の研究 (第3報)
杉本 典夫斎藤 清一
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1953 年 73 巻 7 号 p. 757-760

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Six kinds of compounds, of the following general formulae, were prepared in order to find a powerful analgesic.
For their preparation, Grignard reagent or lithium compound was applied to N-methyl-2-phenacylpiperidine or ethyl N-methylpiperidyl-2-acetate, and the carbinols thereby formed were boiled with hydrochloric acid in glacial acetic acid solution to form the corresponding ethylene compounds.

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