葉酸異性体の合成に就いて

抄録

In view of the fact that a folic acid isomer in which the p-aminobenzoic portion of folic acid had been replaced with m-aminobenzoic acid was antagonistic to folic acid, the biological effect of still another folic acid isomer in which the same portion had been replaced with anthranilic acid seemed to be of interest and its synthesis was carried out by the method elaborated by Uyeo and Mizukami. The compound thereby obtained was a yellowish white amorphous substance, even after repeated purification by reprecipitation, and its biological tests showed it to possess neither the antagonistic nor synergistic action against folic acid.