1953 年 73 巻 7 号 p. 779-780
In order to examine the physiological action, arecoline hydrochloride, arecaidine hydrobromide, and arecaidine hydrochloride were prepared from arecoline hydrobromide. Esterification of arecaidine hydrochloride was carried out by the saturation of dry hydrochloric acid gas in its dehydrated alcohol solution to form ester salts. The free bases of the esters were so unstable that they were derived to stable picrates and again led to the free bases by the use of a liquid chromatography. The bases were then used after neutralization with various acids.