YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
アレカイジン誘導体の合成
塚本 赳夫古森 徹哉
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1953 年 73 巻 7 号 p. 779-780

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In order to examine the physiological action, arecoline hydrochloride, arecaidine hydrobromide, and arecaidine hydrochloride were prepared from arecoline hydrobromide. Esterification of arecaidine hydrochloride was carried out by the saturation of dry hydrochloric acid gas in its dehydrated alcohol solution to form ester salts. The free bases of the esters were so unstable that they were derived to stable picrates and again led to the free bases by the use of a liquid chromatography. The bases were then used after neutralization with various acids.

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