Ninhydrin反応の研究 (第5報)

Ninhydrin反応におけるHydrindantin等の役割

抄録

It seems that the ninhydrin reaction of α-amino acids and amines can be divided into two classes, as pointed out by Moubascher; one route based on the formation of hydrindantin and the other based on the formation of a Schiff base between -NH₂ and ninhydrin. The reaction carried out in pyridine-water system seems to take the latter course. It follows, therefore, that the ninhydrin reduction compound, such as hydrindantin, is a requisite intermediate in the former which is not fundamentally concerned in the latter in which such reduction product merely inhibits oxidative decomposition of the reaction intermediate and accelerates the formation of the Ruhemann purple.