滬紙微量電気泳動法の応用 (第3報)

Diazo反応陽性物質の滬紙電気泳動

抄録

Substances giving positive Pauly's diazo reaction in urine were examined by paper electrophoresis in combination with fractionation by ion exchangers. Urine contains various substances giving positive diazo reaction, other than histidine and tyrosine, and the migration patterns of such substances in the urine of pregnant women, and of patients from morning sickness, pernecious anemia, and Bunti's disease, are qualitatively different. The amount of urochromogen, tyrosine, and histidine was also different. The urine of pregnant woman used in the present experiment did not show as marked an increase histidine as has been reported. The urine from leucemia patient contained comparatively large amount of p-hydroxybenzoic acid and extremely small amount of p-hydroxyphenylacetic acid. Marked excretion of β-indoleacetic acid was also observed in such a case.