いわゆる有胞子乳酸菌の製剤学的研究 (第3報)

抄録

A strain, P 43, of the so-called spore-bearing Lactobacillus was examined in vitro and it was found to be strongly resistant to synthetic gastric and enteric juice. It was able to co-exist with the Lactobacillus commonly present in human intestines but its antibacterial action against aneurinase, coli, proteus, pyogenes, and subtilis bacilli was not very marked. In vitro test of this bacillus, by oral administration in man and rats, revealed somewhat different reaction. Enteric fixation of this bacillus was found to require spore-bearing cells and administration of such cells in thiaminase patients was found to have effected complete elimination of thiaminase bacillus shortly after administration and marked decrease of intestinal fermentation.