1956 年 76 巻 6 号 p. 644-648
Catalylic reduction of 2-chloro-10-β-cyanoethylphenothiazine in the presence of dimethylamine afforded 2-chloro-10-γ-dimethylaminopropylphenothiazine. The same reduction in the presence of diethylamine, piperidine, or morpholine yielded the corresponding homologs. In these cases, the 10-γ-aminopropyl derivative and bis [2-chlorophenothiazinyl-(10)-propyl] amine were invariably formed as by-products. Reaction of carbazole, indole, or benzimidazole with acrylonitrile gave the N-β-cyanoethyl derivatives whose reduction in the presence of dimethylamine afforded N-γ-dimethylaminopropyl derivatives.