ピリジン誘導体の合成研究第7報
2,4-ルチジンのニトロ化に就いて
1956 年 76 巻 8 号 p. 900-902
詳細
1956 年 76 巻 8 号 p. 900-902
The formation of 3-hydroxy-2, 4-lutidine by the application of acetic anhydride to 2, 4-lutidine-1-oxide was found to have been erroneous. The product was found to be 5-hydroxy-2, 4-lutidine by later syntheses of 3- and 5-hydroxy-2, 4-lutidine by the nitration of 2, 4-lutidine and reduction and diazotization of the 3- and 5-nitro-2, 4-lutidines obtained, after each had been isolated. Diazotization of 3- and 5-amino-2, 4-lutidine afforded, besides the phenolic bases, 3H-1, 2, 6-triaza-7-methylindene from the 3-nitro compound and 3H-1, 2, 6-triaza-5-methylindene from the 5-nitro compound.
