Vitamin B₁及び諸関係化合物の研究 第82報

Disulfide型Thiamine誘導体の熱分解について その3 含硫化合物の添加の影響

抄録

In the thermal decomposition of disulfide-type thiamine derivatives in isobutanol, the addition of dialkyl disulfide, sulfur, or bis (2-hydroxyethyl) disulfide resulted in the increased formation of thiochrome (I), thiothiamine (III), or thiamine-thiazolone (II), respectively. The formation of thiamine butyl disulfide (VIII) as an intermediate was observed by the addition of dibutyl disulfide to thiamine disulfide (IV). Therefore, it is assumed that the addition of dialkyl disulfide has effected change of the usual decomposition route of (IV) to the decomposition of thiamine alkyl disulfide and resulted in the formation of a different product.