メラニン生成の抑制剤に関する研究 (第1報)

チロジナーゼ活性に対する銅結合試薬の効果

抄録

Many reports have been published regarding suppressive agent for melanin formation but they do not agree in various points and experimental conditions vary with each worker that their results cannot be compared. In order to make comparative examinations on the known suppression agents as well as some compounds thought to be of interest in this direction under the same experimental conditions, present series of experiments were undertaken. Effect of 14 kinds of copper-combining agents, chiefly chelation agents, on potato tyrosinase was measured by the Warburg manometric technique and results are given in Figs. 1 to 14 and in Table I.