クマリン誘導体の研究 (第16報)

ナフトクマリン及びそのピロン核-4-メチル誘導体とそれ等の還元生成物の駆虫作用

抄録

In vitro anthelmintic tests were carried out on naphthocoumarins, its pyrone-ring 4-methyl derivatives, and their reduction products (I to IX), in order to find relationship between chemical structure and anthelmintic effect. Of these, (IVb), (Va and b), and (VIIIa and b) were found to effect revolving motion and curling-up of ascaris, as with santonin, the action especially marked in (IVb).