1957 年 77 巻 9 号 p. 1007-1011
When aqueous solution of the sodium salt of thiol-type thiamine is warmed, there is an evolution of hydrogen sulfide and butanolic extract of this reaction solution affords a new substance of m. p. 171-172°. The molecular formula of this substance, C12H16O2N4, agrees with those of a compound formed by the liberation of H2S from thiamine. A new substance of m. p. 238° is obtained similarly from the 5-methyithiazolium homolog (II) of thiamine. These substances were assumed to be a pyrimidodiazepine compounds (V and VI) from the infrared spectral measurements, chemical reactions, and syntheses of their decomposition products.