1957 年 77 巻 9 号 p. 941-943
A new coumarin compound, glabra-lactone, had been isolated earlier from the root of Angelica glabra MAKINO and its structure had been proposed. Later, following several substances were obtained from the mother liquor after separation of glabra-lactone. White crystals (A), m. p. 256-257° (corr.), C11H8O4; white crystals (B), m. p. 83-84°, C16H15O3; a small amount of phenolic substance (C), m. p. 166-167°, C15H16O5; acid (D), m. p. 63-64°, C5H8O2; and a liquid acid (E), b.p18 85-91°. (A) was found to be identical with angelical, isolated from the root of A. pubescens MAXIM., found to be 7-methoxy-6-coumarinaldehyde. (B) was identified as osthol from its melting point, composition, and result of chromium trioxide oxidation. (C) exhibits marked bluish fluorescence under ultraviolet light and was assumed to be a phenolic coumarin derivative, but no detailed examination was made. (D) and (E) were considered to be tiglic and angelic acids from their p-bromophenacyl esters. Umbelliferone was detected by microchemical method but it was not isolated as crystals. This is the first time that osthol had been isolated from Japanese umbelliferous plants.