粉末性製剤の安定性に関する研究 (第4報)

吸着剤によるビタミンB₁の分解 その2

抄録

Since it was found that the marked decomposition of thiamine in thiamine-talc powders, in the presence of moisture, was due to adsorption of thiamine on talc, examinations were made on compounding of other adsorbents, such as silica gel, alumina, and aluminum silicate. It was thereby found that decomposition of thiamine occurred, both in suspension and compounded powders, in accordance with adsorptive power of adsorbents. Determination of thiamine in suspension samples was carried out by separatory determination of thiamine in solution and that adsorbed on the adsorbent to find the distribution and change of thiamine in the sample.