YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
ステロイドホルモンと血清蛋白の関係 (第6報)
蛋白結合ステロイドの物理化学的性質 (3)
滝川 泱男
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ジャーナル フリー

1958 年 78 巻 11 号 p. 1296-1301

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Effect of infrared or ultraviolet irradiation on the combination of steroidal hormones with bovine serum albumin or globulin was examined. Ultraviolet irradiation resulted in decreased amount of the combination, with decrease of 2nd wave and increase of 3rd wave in polarogram, both with serum albumin and globulin. Irradiation of infrared ray effected marked decrease of the 2nd wave and combination with steroid was almost nil. The effect of ultraviolet ray on the 3rd wave was greater that of infrared ray while the effect of the infrared ray was greater on the 2nd wave. Serum albumin was found to be affected more than serum globulin. The steroid combined with serum albumin was not separated by ultraviolet ray but was separated by infrared ray, but when it was combined with serum albumin free steroid combined with serum albumin was produced by both ultraviolet ray (especially that in a shorter wave-length region) and infrared ray. The amount of steroid generated by ultraviolet irradiation increaseswith length of irradiation time but no periodical increase was observed by infrared irradiation.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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