YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
抗白癬菌剤の研究 (第1報)
2-メルカプトベンズイミダゾール誘導体の合成並びにその抗白癬菌作用
中島 正太郎田中 一郎赤 輝也安茂 寿夫
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1958 年 78 巻 12 号 p. 1378-1382

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In order to examine the action of benzimidazoles against Trychophyton, 2-alkylthiobenzimidazole derivatives with thioether linkage in 2-position were prepared and their in vitro effect against Trychophyton was examined. These compounds were synthesized by the condensation of 2-mercaptobenzimidazoles with alkyl halide. Some considerations were made on the relationship between chemical structure and antifungal activity.

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