YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
フェナチンの研究 (第16報)
フェナチン誘導体の黄色ブドー状球菌に対する抗菌性と金属イオンの影響
吉岡 一郎上原 寿美子
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1958 年 78 巻 4 号 p. 351-352

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Antibacterial action of 21 kinds of phenazine and phenazine N-oxide derivatives were examined together with the effect of copper on such action. Copper was found to fortify the antibacterial action in 1-hydroxy- and 1, 6-dihydroxyphenazine with hydroxyl radical in α-position but in N-oxide derivatives, such fortifying action of copper was not observed even with those having hydroxyl radical in α-position. As for effect of metals other than copper, a slight fortifying action was seen in zinc, but there was no effect in iron (II) and cobalt.

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