1958 年 78 巻 4 号 p. 376-380
Ethyl 2-methyl-6-benzothiazolecarboxylate was principally prepared by thiocyanation, reduction, and ring formation from thiazole with acetic anhydride in the presence of zinc dust from ethyl p-aminobenzoate. 2-Methyl-6-benzothiazolecarbo-hydrazide was readily synthesized by condensation of the above ethyl ester with hydrazine hydrate. The acid hydrazide obtained was condensed with ten organic acid chlorides. The ten new condensed products so obtained were submitted to bacteriological screening in order to find new antifungal and antitubercal agents. Ethyl 2-amino-6-benzothiazolecarboxylate from ethyl 3-thiocyano-4-aminobenzoate was prepared only by fusion under intramolecular condensation.