YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
含窒素環化合物の合成 (第109報)
ベンゾチアゾール誘導体について その10
高橋 酉蔵岡田 寿太郎上田 善子
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1958 年 78 巻 4 号 p. 437-439

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In order to study the chloropromazine-like action, we synthesized 2-imino-3-(2-dimethylaminoethyl) benzothiazolines and 2-imino-3-(3-dimethylaminopropyl) benzothiazolines by the condensation of 2-aminobenzothiazoles and 2-(dimethylamino) ethyl-, 3-(dimethylamino) propyl chloride hydrochloride. In comparison to them, we synthesized also 2-(2-dimethylaminoethyl)-, 2-(3-dimethylaminopropyl)-aminobenzothiazole by the condensation of 2-(dimethylamino) ethyl-, 3-(dimethylaminopropyl)-amine and 2-bromobenzothiazoles which were obtained from 2-aminobenzothiazoles by Craig's reaction.

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