1958 年 78 巻 5 号 p. 450-454
A total of 92 kinds of compounds selected from 3-methyl-5-pyrazolone, antipyrine, thiopyrine, phthalazine, and quinazoline series, whose effect against human tubercle bacilli had not been tested, were submitted to in vitro tests. 4-Hydrazinoquinazoline was found to inhibit growth in a concentration of 6.25γ/cc., while others showed no observable effect. Thirteen kinds of 4-hydrazinoquinazoline derivative were newly synthesized and their growth inhibitory action was tested with human type tubercle bacilli.