YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
2-Amino-4-phenylthiazole誘導体の合成並びに抗微生物性
上田 文雄
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1959 年 79 巻 10 号 p. 1248-1252

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Thirty kinds of compounds with 2-amino-4-phenylthiazole as the parent compound were synthesized in three series of 2-acylamino-4-phenylthiazole with C2-C16 acyl group, 2-acylamino-4-(p-tolyl) thiazole, and 2-amino-4-(p-alkylphenyl) thiazole with C1-C12 alkyl group. None of these compounds had powerful antitubercular activity but 2-amino-4-phenyl-, 2-amino-4-(p-tolyl)-, and 2-amino-4-(p-decylphenyl) thiazoles showed weak activity in vivo against the Nakayama strain of Japanese B encephalitis virus.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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