1960 年 80 巻 1 号 p. 69-71
1-(5-Nitro-2-furfurylideneamino)-5-alkylhydantoin, an alkylated derivative of nitrofurantoin known as the urethral antiseptic, was prepared. Of these compounds, the isobutyl derivative showed growth inhibition against H37Rv strain of tubercle bacilli in 3γ/cc. concentration. These compounds in general had strong antifungal activity against Trichophyton and Microsporum spp.