溶解補助剤の研究 (第1報)
酸アミド類の溶解補助作用について
1960 年 80 巻 1 号 p. 86-91
詳細
1960 年 80 巻 1 号 p. 86-91
In order to make systematic examination of solubilizing action of acid amides, the strength of solubilizing action and relationship in the concentration of solubilizing agent and solubilizate were examined with 17 kinds of compounds possessing hydroxyl, amino, or carbonyl as the solubilizate, and five kinds of amide, urea, acetamide, cyanoacetamide, nicotinamide, and isonicotinamide, as the solubilizing agent. The order of this strength was: isonicotinamide ≅ nicotinamide>>cyanoacetamide>>acetamide≅urea. It was found that the volubility of the solubilizate increased in proportion to the concentration of solubilizing agent, as indicated in Figs. 1 and 2.
