YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Studies on the Metabolism of Sulfisoxazole. I
On the Excrements in the Human Urine after Administration of Sulfisoxazole
Toyozo UnoMasao Kono
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1960 Volume 80 Issue 2 Pages 201-204

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Abstract
Biological product of sulfisoxazole excreted in the urine after its oral administration was examined chiefly through paper chromatography and paper electrophoresis. It was thereby found that the substances excreted are sulfisoxazole, acetylsulfisoxazole, sulfanilamide, sulfisoxazole-N-sulfonate, and sulfisoxazole-N-glucuronide. Isolation of the substances excreted into the urine was carried out and sulfisoxazole, acetylsulfisoxazole, and an unknown substance were isolated. Other substances were in too minute a quantity or too labile to be isolated.
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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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