YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
ニコチン酸N-オキサイドの生物学的活性 (第3報)
微生物におけるニコチン酸N-オキサイドの活性
辰巳 煕金光 修
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1961 年 81 巻 12 号 p. 1762-1767

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Nicotinic acid N-oxide is utilized, although to a very small extent, by Lactobacillus arabinosus and Leuconostoc mesenteroides which require nicotinic acid. It was also found that nicotinic acid N-oxide may be substituted to a certain extent for nicotinic acid in three strains of coli bacillus mutants requiring nicotinic acid. Examination of baterial enzymes in these microörganisms suggested that these organisms adaptively form enzyme systems that reduce the N-oxide on addition of nicotinic acid N-oxide and utilize the nicotinic acid thereby formed.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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