1961 年 81 巻 2 号 p. 170-172
Although separately determination of l-methylephedrine from l-ephedrine or d-pseudoephedrine was found possible by the use of partition or adsorption chromatography, l-ephedrine and d-pseudoephedrine could not be separated by these procedures. Their separation was successfully effected by the use of salting-out chromatography. A column (20×500mm.) of Dowex-50 X 2 (200-400 mesh) carrying the sample was developed with 0.1M tripotassium phosphate to separate the two alkaloids and each alkaloid was determined by nonaqueous titration after extraction with chloroform.
Combination of the method described in the preceding paper and the present one enables separatory determination of l-methylephedrine, l-ephedrine, and d-pseudoephedrine.