ジギタリスに関する研究 (第7報)

ジギトキシンのアセチル誘導体

抄録

Two new acetyl derivatives of digitoxin, diacetyldigitoxin (III) and triacetyldigi-toxin (IV), were prepared by selective acetylation of digitoxin followed by chromatography on alumina. Tetraacetyldigitoxin (V) was also obtained in a crystalline form for the first time. Physical constants and color reaction of these three acetates were examined. Probable structures of the new acetates (III and IV) are given on the basis of the results of paper chromatography and mild acid hydrolysis.