ハスNelumbo nucifera GAERTN.のアルカロイド (第2報)
Nornuciferineの構造
1961 年 81 巻 7 号 p. 942-947
詳細
1961 年 81 巻 7 号 p. 942-947
Roemerine, nuciferine, and nornuciferine, a nornuciferine, a new aporphine-type tertiary phenolic base, were isolated from the leaves and petioles of domestic lotus, Nelumbo nucifera GAERTN. (Japanese name, “Hasu”). The composition of this base corresponded to C18H19O2N=C16H12(O-CH3)(OH)(N-CH3) and O-methylnornuciferine was found to be entirely identical with nuciferine (1, 2-dimethoxyaporphine) (I). Consequently, it was found that the formula (II) or (III) would be forwarded for nornuciferine.
In the present series of work, the product obtained by degradation of O-ethylnornuciferine, methoxy-ethoxyphenanthrene, was proved to be 3-ethoxy-4-methoxyphenanthrene (XVb) and, consequently, the structure of nornuciferine was established as 1-methoxy-2-hydroxyaporphine (III).
