1-Phenacylpyridinium Bromideによる2-Phenylindole誘導体の新合成法
1961 年 81 巻 9 号 p. 1353-1356
詳細
1961 年 81 巻 9 号 p. 1353-1356
The formation of 2-phenylindole by heating of 1-phenacylpyridinium bromide and aniline at high temperatures was confirmed. Examination of reaction conditions showed that the reaction of 1 mole of 1-phenacylpyridinium bromide and 2 moles of aniline in N, N-dimethylaniline, by heating at 200° for 2 hours, gave the product in 83% yield. It was revealed through the use of various amines in place of aniline that 2-phenylindole derivatives are formed from aromatic primary amines in which the ortho position of amino group is not substituted.
