Gougerotinの化学構造の研究 その8

C物質の糖部分の構造 (iii) アミノ基の位置

抄録

In order to determine the position of the amino group in the sugar portion of the C substance, Ninhydrin oxidation of hexosamine and CR substance was carried out but pentose was not detected in either of these reaction solutions, showing that there are no amino group in 2- or 5-position of the hexose. Periodate oxidation of the C substance (VII), CR substance (VIII), seryl-C substance (IX), and N-acetylated derivatives (XI and X), and examination of their products showed that the sugar moiety in the C substance takes a pyranose structure and that the amino group is in its 3-position. Consequently, the planar structure of the C substance was assumed to be 1-(1-cytosinyl)-3-amino-1, 3-dideoxyhexopyranuronic acid (VII).