N-(3,4-Dimethoxyphenethyl) ureaのBischler-Napieralski反応
1962 年 82 巻 3 号 p. 352-355
詳細
1962 年 82 巻 3 号 p. 352-355
N-(3, 4-Dimethoxyphenethyl) urea, obtained by heating of 3, 4-dimethoxyphenethyl-amine hydrochloride with urea, was cyclized to 1-amino-6, 7-dimethoxy-3, 4-dihydroisoquinolinium chloride (II or II′) with phosphorous pentoxide and phosphoryl chloride. (II) or (II′) gave N-(2-cyano-4, 5-dimethoxyphenethyl) benzenesulfonamide (III) when it was treated with benzenesulfonyl chloride in alkaline solution.
