アルキルビニルエーテルおよびその誘導体を利用する諸反応について (第8報)
塩素を含有する一, 二の化合物の合成
1962 年 82 巻 3 号 p. 457-459
詳細
1962 年 82 巻 3 号 p. 457-459
Reaction of vinyl ether and acrolein to form 2-alkoxy-3, 4-dihydro-2H-pyran and introduction of chlorine in the cold, in the presence of sodium carbonate and alcohol, afforded 2, 6-dialkoxy-3-chlorotetrahydropyran in ca. 72% yield. Its oxidation with nitric acid gave 2-chloroglutaric acid in 74% yield. Reaction of vinyl ether and carbon tetrachloride, with benzoyl peroxide as a catalyst, and acetalization of its product gave 3, 3, 3-trichloropropionaldehyde acetal. Catalytic reduction of this acetal over palladium-charcoal in ammonia alkalinity afforded 3, 4-dichloro-1, 1, 6, 6-tetraalkoxy-3-hexene. 3, 3, 4, 4-Tetrachloro-1, 1, 6, 6-tetraälkoxyhexane was also obtained from this reaction according to the amount of ammonia used.
