皮膚真菌症の実験化学療法的研究 (第2報)
p-Arylazophenol系化合物の真菌に対する抗黴作用についての検索
1962 年 82 巻 5 号 p. 719-725
詳細
1962 年 82 巻 5 号 p. 719-725
In a search for antimicrobial substance among azo compounds, some examinations were made on compounds with p-phenylazophenol structure and in which vitro group had been introduced. In vitro growth-inhibitory tests were carried out on 33 compounds of p-(p-nitrophenylazo)phenol introduced with nitro, halogen, or other substituents, and 14 kinds of azophenol compounds containing a nitro group, using six kinds of fungi, Trichophyton asteroides, T. interdigitale, T. schoenleinii, Microsporum gypseum, Epidermophyton floccosum, and Candida albicans. It was found that 3-Chloro-and 3-bromo-4-(p-nitrophenylazo)phenol had growth-inhibitory action against all the fungi tested in a high dilution of 1:2, 560, 000 to 1:10, 240, 000.
