Polyhydroxyanthraquinone 類の合成研究 (第1報)
2-置換1,3,6,8-tetrahydroxyanthraquinone 類の合成
1962 年 82 巻 7 号 p. 959-963
詳細
1962 年 82 巻 7 号 p. 959-963
The Friedel-Crafts reaction of γ-methylresorcinol and 3, 5-dimethoxyphthalic anhydride gave 2-(3-methyl-2, 4-dihydroxybenzoyl)-3, 5-dimethoxybenzoic acid and dehydrative cyclization of its methyl derivative afforded 1-hydroxy-2-methyl-3, 6, 8-trimethoxyanthraquinone in a good yield. This anthraquinone compound was derived to 1, 3, 6, 8-tetramethoxy-2-anthraquinonecarboxylic acid in five steps. The position of the hydroxyl groups in this acid was confirmed with tetrahydroxyanthraquinone formed by its demethylation.
