YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
ツキヨタケからのLampterolの単離
中西 香爾大橋 守鈴木 冲多田 愈山田 泰司稲垣 清二郎
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1963 年 83 巻 4 号 p. 377-380

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An antitumor substance, Lampterol (C15H20O4) has been isolated from a japanese poisonous mushroom Lampteromyces japonicus (KAWAM.) SING., in an overall yield of 2×10-3% from the raw mushroom. The procedure is described in Chart 1. The activity of lampterol as measured against Ehrlich ascitic tumor in mice is 120γ/kg., and the toxicity as measured by intraperitoneal injection into normal mice is 5mg./kg. Lampterol gave a diacetate. Lampterol is isomerized to isolampterol when passed through an alumina column; isolampterol gave a triacetate.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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