セリ科植物の生薬学的研究 (第19報)
白〓の研究 その4 日本産および中国産白〓のクマリン成分について
1963 年 83 巻 6 号 p. 606-610
詳細
1963 年 83 巻 6 号 p. 606-610
The crude drug Chinese Byaku-shi, the dried root of Angelica dahurica BENTH. et HOOK. var. pai-chi KIMURA, HATA et YEN (Umbelliferae), afforded five kinds of furocoumarins, oxypeucedanin (I), isoimperatorin (II), imperatorin (III), phellopterin (IV), and byak-angelicin (V), and Jananese Byaku-shi, the dried root of A. dahurica BENTH. et HOOK. var. dahurica, afforded I, III, and IV in addition to V and byak-angelicol (VI), which had been found first by Noguchi from the same drug, by the process shown in Chart 1.
In the present experiments, it was found that through column chromatography over silicic acid (Mallinckrodt) VI was converted into V by the opening of the epoxide ring in the side chain. By thin-layer chromatography, a spot identified as VI was detected from the ether extract of Chinese Byaku-shi but V was not detected, contrary to the result mentioned above.
Therefore, it is considered that almost all of V isolated from Chinese Byaku-shi had originally been contained in the drug in the form of VI.
The present result seems to support the proposal of Kimura and others assigning a local variety of A. dahurica BENTH. et HOOK. for the original plant of Chinese Byaku-shi.
