YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
鎮痛剤の合成研究 (第2報)
N-(Dimethylaminoalkyl) aniline系化合物の合成と薬理作用
気賀沢 和雄菅原 宏柊木 峯治府川 和永
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1963 年 83 巻 7 号 p. 696-700

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In continuation to the previous report, aminobenzene derivatives, represented by the general formula, Y-C6H4NR-CH2CH2CH2N(CH3)2, Y-C6H4NRCH2CH2N(CH3)2 (Y=H, OC2H5; R=H, CH3, CH2C6H5, COCH3, COC6H5) being also ethylenediamine derivatives, were synthesized as is shown in Table I and II. All of the analgesic activities were examined and some of the superior derivatives to aminopyrine were shown in Table III and IV.

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