1963 年 83 巻 9 号 p. 838-844
Preliminary experiments revealed that (2-bromo-4, 5-dimethoxyphenyl) acetic acid hydrazide possessed an anti-cancer action. Therefore, various hydrazide derivatives were synthesized and their anti-cancer action was examined. None of the compounds synthesized, i.e. 2-halogeno-4, 5-dialkoxybenzoic acid hydrazide, (2-halogeno-4, 5-dialkoxyphenyl) acetic acid hydrazide, 2-halogeno-4, 5-dialkoxyhydrocinnamic acid hydrazide, and their related compounds, showed any better effect than 6-mercaptopurine.