YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
抗ガン剤に関する研究 第8報
(2-ブロモ-4,5-ジメトキシフェニル) 酢酸ヒドラチッドと各種カルボニル化合物との反応成績体およびその抗ガン性について
亀谷 哲治梅沢 修八木 治彦石黒 正子水野 伝一
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1963 年 83 巻 9 号 p. 844-847

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Condensation products of (2-bromo-4, 5-dimethoxyphenyl) acetic acid hydrazide and various carbonyl compounds were prepared and their anti-cancer activity was examined. Some anti-cancer effect was observed in the condensation product with isovanillin. The reaction of the above hydrazide with chloral or bromal in alcohol was found to result in dehydrazino reaction to form ethyl (2-bromo-4, 5-dimethoxyphenyl) acetate. The mechanism of this reaction is now being examined.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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