1963 年 83 巻 9 号 p. 844-847
Condensation products of (2-bromo-4, 5-dimethoxyphenyl) acetic acid hydrazide and various carbonyl compounds were prepared and their anti-cancer activity was examined. Some anti-cancer effect was observed in the condensation product with isovanillin. The reaction of the above hydrazide with chloral or bromal in alcohol was found to result in dehydrazino reaction to form ethyl (2-bromo-4, 5-dimethoxyphenyl) acetate. The mechanism of this reaction is now being examined.