YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
ハイドロオキシフルオランおよびその誘導体の有機試薬としての利用研究 (第5報)
3´,4´,5´,6´-Hydroxyfluoran系誘導体の金属指示薬への応用
森 逸男
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ジャーナル フリー

1965 年 85 巻 8 号 p. 686-692

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From the color reaction of hydroxyfluorans and its halogen derivatives with metal ions, 3′, 4′, 5′, 6′-and 2′, 3′, 6′, 7′-tetrahydroxyfluoran, and 2′-, 4′-halo-and 2′, 4′-dihalo-3′, 6′, 7′-and 3′, 5′, 6′-trihydroxyfluorans were found to undergo sensitive coloration. Examinations were made on the color reaction of 3′, 5′, 6′-trihydroxyfluoran, 3′, 4′, 5′, 6′-tetrahydroxyfluoran, amino acetic acid and iminodiacetic acid complexones of hydroxyfluorans, and their derivatives substituted in 2′-, 4′-, or 2′, 4′-positions with chlorine, bromine, and/or iodine with metal ions (Hg2+, Th3+, Bi3+, Zr4+, In3+, Ce3+, La3+, Cd2+, Zn2+, Cu2+, Co2+, Ni2+, Ba2+, Sr2+, Ca2+, Mg2+). 3′, 4′, 5′, 6′-Tetrahydroxyfluoran, hydroxyfluoran complexones, and bromo and chloro derivatives of 3′, 5′, 6′-trihydroxyfluoran were found to form colored complex in high sensitivity, and the tone of color was deep, especially in the case of 2′, 4′-disubstituted 3′, 5′, 6′-trihydroxyfluoran, and change of color in the chelate titration was also very sensitive. Coloration of iodine-substituted 3′, 5′, 6′-trihydroxyfluoran with a metal ion was hypsochromic and color change was also indistinct. Good indicator quality was found in Bi3+, Hg2+, Th3+, Cd2+, Co2+, Zn2+, Cu2+, Ni2+, La3+, Pb2+, and rare earth metal ions.

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