Abstract
Comparative examinations were made on the action mechanism of leukocytosis promoting activity of Parotin isolated from the bovine parotid gland and S-Parotin isolated from the bovine submaxillary gland. The leukocytosis promoting activity of Parotin and S-Parotin is chiefly carried on by granulocytes, and effects decrease of lymphocytes and monocytes. Since this activity originating from granulocytes is observed in the rabbit serum 2 hours after the administration of Parotin or S-Parotin, it is considered that a leukocytosis promoting factor is produced in vivo after such administration, as in the case of Saliva Parotin A.