YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
脂肪族アチル-アミノ酸N-アチルアミノ酸(第2報)
須山 正豊田 猛金尾 清造
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1966 年 86 巻 10 号 p. 967-972

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Some of the alithatic acylamino acids show notable surface activitv or antibacterial activity. Direct Schotten-Baumann reaction of amino acids afforded N-lauryl-L-threonine (80% yield), O, N-dilauryl-L-tyrosine (50%), and N, N-dilauryl-L-lysine (53%). N-Stearyl-L-glutamic acid was obtained by the application of stearyl chloride to diethyl L-glutamate in dimethylformamide, in the presence of pyridine. In this way, about 50 kinds of aliphatic acylamino acids were obtained from various amino acids, and C<8∼22> saturated acids and some unsaturated acids.

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