アルキルアミノ酸(第6報)
1966 年 86 巻 11 号 p. 1105-1108
詳細
1966 年 86 巻 11 号 p. 1105-1108
Action of allyl bromides, 2-methylthioethyl bromide, and benzyl chloride on amino acids was examined. Acid and basic amino acids do not undergo allylation, and acid amino acids are not 2-methylthioethylated. Acid amino acids form disubstituted compounds by benzylation. The N, N-dibenzylglutamic acid reported earlier as a racemate was found to be a laevorotatory compound with [α]21D-15.42°(0.2N NaOH). This reaction was accompanied by the byproduct formation of 1-benzyl-5-oxo-L-pyrrolidinecarboxylic acid, m.p. 160°, [α]15D+19.94°(2N HCl). In the case of cystine, the products were monosubstituted compounds.
