1966 年 86 巻 12 号 p. 1191-1196
In order to know whether carbamate N-glucuronides were metabolic end-products or not, the present experiment was carried out, using sodium meprobamate N-glucopyranosiduronate and urethan N-glucopyranosiduronic acid. It was found that β-glucuronidase prepared from rabbit liver did not act on these N-glucuronides in 0.1M acetate buffer at pH 4.4 to 5.6, and that most of the glucuronides administered intravenously into rabbits was recovered unchanged in the urine excreted within 24 hours.