1966 年 86 巻 12 号 p. 1220-1223
In relation to the study on the metabolic fate of carbamate N-glucuronides, pharmacological actions of meprobamate and urethan N-glucuronides were examined comparing with those of carbamates themselves. Neither competition to convulsant action of strychnine nor prolongation of hypnotic action of pentobarbital was observed in both N-glucuronides, but was found in carbamates themselves. It was demonstrated, however, that both N-glucuronides were distributed considerably well into the brain.