粉粒体の圧縮成型に関する研究(第1報) : 圧縮設計のための無次元数の提案ならびに各種圧縮式への導入

抄録

Many difficulties occur as for instance consideration on packing and compression conditions on compression designs and no report has been established thus subject. We propose a dimensionless number [numerical formula], where, m is the packed weitht, D is the diameter of a flat type compression punch, S is the tablet thickness and ρ is the density of the packed substance. It is possible to express several compression equations by N_b, because the relation between N_b and porosity is [numerical formula]. In the middle pressure region used in usual pharmaceutical tableting process Balshin-type-plot (log P=f(N_b)) is suitable for compression designs, in the low pressure region Kawakita-type-plot ([numerical formula]) is better, and in the high pressure region, Athy-Konopicky-type-plot (P=log n) is more convenient.