ヘテロ環化合物の研究(第5報) : 3,4-ジヒドロキシ-2,5-ジカルボメトキシフラン誘導体の合成

抄録

Synthesis of dimethyl 3, 4-dihydroxy-2, 5-furandicarboxylate (I) was examined. Hydrolysis of I gave a new compound, 3, 4-dihydroxy-2, 5-furandicarboxylic acid. Alkylation and acylation of I afforded a dozen of new compounds. It was found that hydrolysis of I, dimethyl 3, 4-bis(5-methyl-2-furoyloxy)-2, 5-furandicarboxylate, and dimethyl 3, 4-bis(5-nitro-2-furoyloxy)-2, 5-furandicarboxylate respectively afforded the decomposition products, 2-furoic acid, 3, 4-dihydroxy-2-carboxy-5-carbomethoxyfuran, dimethyl 3, 4-dihydroxy-2, 5-furandicarboxylate, and 5-methyl-2-furoic acid. Hydrolysis of dimethyl 3, 4-dibenzyloxy-2, 5-furandicarboxylate gave 3, 4-dibenzyloxy-2, 5-furandicarboxylic acid.